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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 14.55
Human Site: S491 Identified Species: 29.09
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 S491 G F N E Y F P S R P H P G S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 N473 L A D Y F G A N R H P A G L T
Dog Lupus familis XP_536720 1330 145448 S566 G F N E Y F P S R P H P G S L
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 S492 G F S E Y F P S R P H P G S L
Rat Rattus norvegicus XP_002726668 1257 138805 S492 G F S E Y F P S R P H P G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 Q248 S S S A C R M Q G P R E G V A
Chicken Gallus gallus XP_417551 908 100815 V177 Q N L A V C H V N D Q I Y Y K
Frog Xenopus laevis B7ZRU9 1055 118966 P324 P F I P P A S P V K G L P G V
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 L422 N G N I G S S L S S Q S E E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 R259 P C K Q C A L R F C H R P L L
Honey Bee Apis mellifera XP_001121599 1541 171480 G532 F Y P T S L M G P Y P G I F P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 T971 T C G Q T F S T V T S L N K H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 13.3 100 N.A. 93.3 93.3 N.A. 13.3 0 6.6 6.6 N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 N.A. 33.3 100 N.A. 100 100 N.A. 20 0 13.3 6.6 N.A. 20 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 17 9 0 0 0 0 9 0 0 9 % A
% Cys: 0 17 0 0 17 9 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 34 0 0 0 0 0 0 0 9 9 9 0 % E
% Phe: 9 42 0 0 9 42 0 0 9 0 0 0 0 9 0 % F
% Gly: 34 9 9 0 9 9 0 9 9 0 9 9 50 9 0 % G
% His: 0 0 0 0 0 0 9 0 0 9 42 0 0 0 9 % H
% Ile: 0 0 9 9 0 0 0 0 0 0 0 9 9 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 9 0 0 0 9 9 % K
% Leu: 9 0 9 0 0 9 9 9 0 0 0 17 0 17 42 % L
% Met: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 25 0 0 0 0 9 9 0 0 0 9 0 9 % N
% Pro: 17 0 9 9 9 0 34 9 9 42 17 34 17 0 9 % P
% Gln: 9 0 0 17 0 0 0 9 0 0 17 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 9 42 0 9 9 0 0 0 % R
% Ser: 9 9 25 0 9 9 25 34 9 9 9 9 0 34 0 % S
% Thr: 9 0 0 9 9 0 0 9 0 9 0 0 0 0 9 % T
% Val: 0 0 0 0 9 0 0 9 17 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 34 0 0 0 0 9 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _